diff --git a/RELEASENOTES.md b/RELEASENOTES.md
index ecf4473c6c..a8c85406c1 100644
--- a/RELEASENOTES.md
+++ b/RELEASENOTES.md
@@ -45,6 +45,8 @@
 *   DRM:
     *   Work around a bug in the Android 13 ClearKey implementation that returns
         a non-empty but invalid license URL.
+    *   Fix `setMediaDrmSession failed: session not opened` error when switching
+        between DRM schemes in a playlist (e.g. Widevine to ClearKey).
 *   DASH:
     *   Parse `EventStream.presentationTimeOffset` from manifests
         ([#10460](https://github.com/google/ExoPlayer/issues/10460)).
diff --git a/libraries/exoplayer/src/main/java/androidx/media3/exoplayer/mediacodec/MediaCodecRenderer.java b/libraries/exoplayer/src/main/java/androidx/media3/exoplayer/mediacodec/MediaCodecRenderer.java
index b6e651419c..79c3b9ca7a 100644
--- a/libraries/exoplayer/src/main/java/androidx/media3/exoplayer/mediacodec/MediaCodecRenderer.java
+++ b/libraries/exoplayer/src/main/java/androidx/media3/exoplayer/mediacodec/MediaCodecRenderer.java
@@ -2094,6 +2094,11 @@ public abstract class MediaCodecRenderer extends BaseRenderer {
 
     // Note: Both oldSession and newSession are non-null, and they are different sessions.
 
+    if (!newSession.getSchemeUuid().equals(oldSession.getSchemeUuid())) {
+      // MediaCrypto.setMediaDrmSession is unable to switch between DRM schemes.
+      return true;
+    }
+
     if (Util.SDK_INT < 23) {
       // MediaCrypto.setMediaDrmSession is only available from API level 23, so re-initialization is
       // required to switch to newSession on older API levels.